The Ala55Val and -866G>A polymorphisms of the UCP2 gene could be biomarkers for weight loss in patients who had Roux-en-Y gastric bypass
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- 作者：Carolina F. Nicoletti ; Ph.D.a ; Ana Paula R.P. de Oliveira ; R.D.b ; Maria José ; F. Brochado ; Ph.D.a ; Marcela A.S. Pinhel ; Ph.D.a ; Bruno A.P. de Oliveira ; M.S.a ; Julio S. Marchini ; Ph.D.a ; José ; E. dos Santos ; Ph.D.a ; Wilson Salgado Jr. ; Ph.D.c ; Nathalia Moreno Cury ; M.S.d ; Luiza Ferreira de Araú ; jo ; M.S.d ; Wilson A. Silva Jr. ; Ph.D.d ; Carla B. Nonino ; Ph.D.a ; Carla@fmrp.usp.br
- 关键词：Obesity ; Bariatric surgery ; Weight loss ; UCP2 polymorphism ; Biomarker
- 刊名：Nutrition
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：33
- 期：Complete
- 页码：326-330
- 全文大小：236 K
- 卷排序：33
文摘
Genotype analysis showed a greater prevalence of heterozygous for uncoupling protein (UCP)2 polymorphisms. Individuals who carried mutated alleles for UCP2 polymorphisms showed a greater loss of weight and fat-free mass. The mutated alleles for UCP2 polymorphism could be biomarkers of weight loss 1 y after Roux-en-Y gastric bypass.