Contrast agents based on switchable near-infrared fluorescent nanoprobes for highly sensitive optical imaging
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- 作者：Hye Sun Parka ; Mi Young Choa ; Young-Woock Nohb ; Kwan Soo Honga ; kshong@kbsi.re.kr" class="auth_mail" title="E-mail the corresponding author ; Yong Taik Limb ; yongtaik@skku.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：pH-responsive ; Activatable fluorophore ; Nanoparticles ; Indocyanine green ; Molecular imaging
- 刊名：Dyes and Pigments
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：136
- 期：Complete
- 页码：583-589
- 全文大小：1667 K
文摘
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Switchable near-infrared fluorophores showing higher sensitivity were synthesized.
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The signal intensity of pH-responsive fluorophores increased about 11-fold in acidic solution.
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Transition from quenched to de-quenched state recovered fluorescence signal.
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The activatable molecular imaging probes can be used for the labeling of target cells.
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