Non-plaque-forming virions of Modified Vaccinia virus Ankara express viral genes
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- 作者：Anna-Theresa Lü ; lfa ; b ; Astrid Freudensteina ; Lisa Marra ; Gerd Suttera ; b ; gerd.sutter@lmu.de" class="auth_mail" title="E-mail the corresponding author ; Asisa Volza ; b
- 关键词：Poxvirus ; Vaccines ; Virus particles ; Plaque forming units ; Gene expression
- 刊名：Virology
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：499
- 期：Complete
- 页码：322-330
- 全文大小：2544 K
文摘
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Recombinant vaccinia virus MVA preparations contain >70% non-plaque-forming virions.
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Non-plaque-forming particles can enter cells and switch on viral gene expression.
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Non-plaque-forming virions are likely to contribute to vaccine immunogenicity.