High-Affinity Sites Form an Interaction Network to Facilitate Spreading of the MSL Complex across the X Chromosome in Drosophila
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- 作者：Fidel Ramí ; rez1 ; 7 ; Thomas Lingg1 ; 2 ; 7 ; Sarah Toscano1 ; 7 ; Kin Chung Lam1 ; 2 ; 7 ; Plamen Georgiev1 ; Ho-Ryun Chung3 ; Bryan R. Lajoie4 ; Elzo de Wit5 ; Ye Zhan4 ; Wouter de Laat5 ; Job Dekker4 ; 6 ; Thomas Manke1 ; Asifa Akhtar1 ; akhtar@ie-freiburg.mpg.de" class="auth_mail" title="E-mail the corresponding author
- 刊名：Molecular Cell
- 出版年：2015
- 出版时间：1 October 2015
- 年：2015
- 卷：60
- 期：1
- 页码：146-162
- 全文大小：6041 K
文摘
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HAS frequently occur at regions with enriched long-range contacts on the X chromosome
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Global X chromosome architecture is sex- and MSL complex-independent in flies
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roX HAS dynamically organize within the X territory depending on transcriptional status
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The MSL complex uses spatial proximity to spread and affects nucleosome pattern at HAS