The diversity of globin-coupled sensors

详细信息    查看全文

• 作者：Freitas ; Tracey Allen K. ; Hou ; Shaobin ; Alam ; Maqsudul
• 关键词：Globin ; Archaeon ; Heme-based sensor ; Globin-coupled sensor
• 刊名：FEBS Letters
• 出版年：2003
• 出版时间：September 25, 2003
• 年：2003
• 卷：552
• 期：2-3
• 页码：99-104
• 全文大小：648 K

文摘

The recently discovered globin-coupled sensors (GCSs) are heme-containing two-domain transducers distinct from the PAS domain superfamily. We have identified an additional 22 GCSs with varying multi-domain C-terminal transmitters through a search of the complete and incomplete microbial genome datasets. The GCS superfamily is composed of two major subfamilies: the aerotactic and gene regulators. We postulate the existence of protoglobin in Archaea as the predecessor to the chimeric GCS.