Long time remodeling during retinal degeneration evaluated by optical coherence tomography, immunocytochemistry and fundus autofluorescence
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- 作者：Isabel Pinillaa ; b ; c ; isabel.pinilla@telefonica.net" class="auth_mail" title="E-mail the corresponding author ; Laura Ferná ; ndez-Sá ; nchezd ; Francisco J. Segurab ; c ; Ana Isabel Sá ; nchez-Canob ; e ; José ; Manuel Tamaritf ; Lorena Fuentes-Brotob ; g ; Janis T. Eellsh ; Pedro Laxd ; Nicolá ; s Cuencad
- 关键词：Retina ; OCT ; Immunocytochemistry ; P23H ; Retinitis pigmentosa ; Remodeling
- 刊名：Experimental Eye Research
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：150
- 期：Complete
- 页码：122-134
- 全文大小：5021 K
文摘
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We provided a detailed long-term analysis of the course of retinal degeneration in P23H rats.
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Retinal degeneration in P23H was studied with a combination of SLO and OCT imaging, angiography, FAF and IHC.
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Application of noninvasive methods could enable longitudinal studies and decrease the number of animals needed for a study.