Functional connectivity alterations in the motor and fronto-parietal network relate to behavioral heterogeneity in Parkinson's disease
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- 作者：Griet Vervoorta ; griet.vervoort@faber.kuleuven.be" class="auth_mail" title="E-mail the corresponding author ; Kaat Alaertsa ; kaat.alaerts@faber.kuleuven.be" class="auth_mail" title="E-mail the corresponding author ; Aniek Bengevoorda ; aniek.bengevoord@faber.kuleuven.be" class="auth_mail" title="E-mail the corresponding author ; Evelien Nackaertsa ; evelien.nackaerts@faber.kuleuven.be" class="auth_mail" title="E-mail the corresponding author ; Elke Heremansa ; elke.heremans@faber.kuleuven.be" class="auth_mail" title="E-mail the corresponding author ; Wim Vandenbergheb ; wim.vandenberghe@uzleuven.be" class="auth_mail" title="E-mail the corresponding author ; Alice Nieuwboera ; alice.nieuwboer@faber.kuleuven.be" class="auth_mail" title="E-mail the corresponding author
- 关键词：Parkinson's disease ; Resting-state fMRI ; Subtypes ; Heterogeneity ; Motor control
- 刊名：Parkinsonism & Related Disorders
- 出版年：2016
- 出版时间：March 2016
- 年：2016
- 卷：24
- 期：Complete
- 页码：48-55
- 全文大小：1120 K
文摘
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Striatal hypo-connectivity relates to worse motor impairment in PIGD.
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PPN hyper-connections contribute to PIGD pathophysiology.
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IPL-related hyper-connectivity indicates compensatory mechanisms in TD.
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Neural network resting-state FC alterations underscore behavioral heterogeneity in PD.