Young Women with a Long Past of Resistant Hypertension Cured after Surgery of Severe Bilateral Ostial Renal Artery Stenosis

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• 作者：Blandine Simonnet¹ ; Pierre Deharo¹ ; Karim Rouabah² ; Franç ; ois Silhol¹ ; Raphael Soler¹ ; Jean Michel Bartoli² ; Olivier Lé ; vrier² ; Michel Alain Bartoli¹ ; Pierre Edouard Magnan¹ ; Gabrielle Sarlon-Bartoli¹ ; ^{gabrielle.sarlon@ap-hm.fr" class="auth_mail" title="E-mail the corresponding author}
• 刊名：Annals of Vascular Surgery
• 出版年：2016
• 出版时间：July 2016
• 年：2016
• 卷：34
• 期：Complete
• 页码：272.e5-272.e8
• 全文大小：810 K

文摘

Fibromuscular dysplasia (FMD) is an underdiagnosed disease which can affect young people and with poor prognosis such as dissection or aneurysm rupture if unknown. This case illustrates a multi-vessel FMD with symptomatic severe bilateral ostial renal artery stenosis and intracranial aneurysms. One of the original features is a very late delay to diagnosis with 23 years between onset of hypertension and renal stenosis diagnosis, particularly due to lower quality of initial CT scan with milder and uncommon abnormalities. The experiment neuroradiologist had suspected the diagnosis of renal FMD because she developed intracranial aneurysms and he confirmed this diagnosis with an artery renal contrast injection during an intracranial angiogram Because of very tight and short stenosis, surgery was chosen for treatment and permitted the cure of hypertension, with normal home blood pressure after 6 months. Several particularities of FMD were presented in this case: important delay diagnosis due to rare lesion and lower sensitivity of CT in this form, the possibility to perform an angiography in high suspicion of FMD, poor prognosis risk with intracranial aneurisms and premature birth child, and the choice for surgery with cure of hypertension. We thought that hypertension etiologic evaluation must be repeated in case of resistant hypertension in young patients, particularly when they developed intracranial aneurysms.