Specialized refeeding treatment for anorexia nervosa patients suffering from extreme undernutrition

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• 作者：Maria Gabriella Gentile ; Paola Pastorelli ; Raffaella Ciceri ; Giulia Maria Manna ; Simona Collimedaglia
• 关键词：Anorexia nervosa ; Extreme undernutrition ; Refeeding syndrome ; Nutritional rehabilitation
• 刊名：Clinical Nutrition
• 出版年：2010
• 出版时间：October 2010
• 年：2010
• 卷：29
• 期：5
• 页码：627-632
• 全文大小：138 K

文摘

Summary

Background & aims

Refeeding severely malnourished patients with Anorexia nervosa requires specialized in-patient treatment to reduce medical risks, to avoid refeeding syndrome and other life-threatening situations.

Methods

The authors present a retrospective cohort nutritional rehabilitation study of 33 very severe Anorexia nervosa in-patients, aged 22.8 ± 7.6 years (±SD) and with an initial body mass index ≤ 12 kg/m², treated in a specialized Eating Disorders Unit.

Results

Thirty-three female patients were included and treated. Mean BMI increased from 11.3 ± 0.7 Kg/m², to 13.5 ± 1 Kg/m², and mean body weight from 29.1 ± 3.2 Kg to 34.5 ± 3.3 Kg, after 60 days of intensive in-patient treatments (p < 0.0001).

Feeding was carefully instituted; caloric intake levels were established after measuring REE by indirect calorimetry. Nutritional support was initiated with temporary nasogastric feeding in 30 patients, and with oral supplementation in 3 patients.

Vitamins, potassium and phosphate supplements were administered during refeeding. All patients achieved a significant increase in body weight, none developed refeeding syndrome as far as laboratory and clinical investigations were concerned.

Conclusions

Our findings show that, even in cases of extreme undernutrition, if feeding is performed cautiously and in a specialized unit, it is possible to avoid the refeeding syndrome.