ER stress and impaired autophagy flux in neuronal degeneration and brain injury

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• 作者：Yan Yin ; M.D. ; Ph.D^a ; ^b ; ^{yanyin1208@126.com} ; George Sun^b ; Eric Li^b ; Kirill Kiselyov ; Ph.D^c ; Dandan Sun ; M.D. ; Ph.D^b ; ^d ; ^{sund@upmc.edu}
• 关键词：Autophagy ; Brain aging ; Docosahexaenoic acid ; Lysosome ; Stroke ; Traumatic brain injury
• 刊名：Ageing Research Reviews
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：34
• 期：Complete
• 页码：3-14
• 全文大小：2150 K
• 卷排序：34

文摘

Review of ER stress, UPR activation, autophagy, and autophagy flux processes. Changes of autophagy in the aging brain and neurodegenerative diseases. Review of ER stress and autophagy after TBI and ischemic stroke. Summary of effects of DHA on ER stress and autophagy after TBI and ischemia. Effects of DHA in the aging brain and cancer cells.