Glycation in human fingernail clippings using ATR-FTIR spectrometry, a new marker for the diagnosis and monitoring of diabetes mellitus

详细信息    查看全文

• 作者：Renaat Coopman^a ; Thijs Van de Vyver^a ; Antoine Sadiki Kishabongo^b ; Philippe Katchunga^c ; Elisabeth H. Van Aken^d ; Justin Cikomola^c ; Tinne Monteyne^a ; Marijn M. Speeckaert^e ; Joris R. Delanghe^a ; ^{joris.delanghe@ugent.be}
• 关键词：Fingernails ; Fructosamine ; Glycation ; Infrared spectroscopy ; Keratin
• 刊名：Clinical Biochemistry
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：50
• 期：1-2
• 页码：62-67
• 全文大小：683 K
• 卷排序：50

文摘

Fingernail clippings contain ± 85% of keratins, which are prone to glycation. Nail keratin glycation may reflect the average glycemia over the last months. ATR-FTIR spectroscopy could be an alternative technique for diagnosing diabetes.