Novel folic acid conjugated Fe₃O₄-ZnO hybrid nanoparticles for targeted photodynamic therapy

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• 作者：Kunal Patel^a ; Behin Sundara Raj^b ; Yan Chen^b ; Xia Lou^a ; ^{x.lou@curtin.edu.au} ; ^{lizilou7854@gmail.com}
• 关键词：Photosensitiser ; Photodynamic therapy ; Photocatalysts ; Photo-killing ; Cancer targeting
• 刊名：Colloids and Surfaces B: Biointerfaces
• 出版年：2017
• 出版时间：1 February 2017
• 年：2017
• 卷：150
• 期：Complete
• 页码：317-325
• 全文大小：2371 K
• 卷排序：150

文摘

Novel semiconductor photosensitisers (PS) for PDT were synthesised. Photophysical properties, cytotoxicity and phototoxicity were evaluated. Caco-2 cell viability was reduced to 6–11% by photo irradiated nano-PSs. Folic acid conjugation enhanced the photo-killing effect.