A role for multiple estrogen receptors in immune regulation of common carp
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- 作者：Ewa Szwejsera ; Magdalena Maciuszeka ; Ayako Casanova-Nakayamab ; Helmut Segnerb ; B.M. Lidy Verburg-van Kemenadec ; Magdalena Chadzinskaa ; magdalena.chadzinska@uj.edu.pl" class="auth_mail" title="E-mail the corresponding author
- 关键词：Estrogen receptors ; 17β-estradiol ; Immune response ; Monocyte/macrophage ; GPR30 ; Carp
- 刊名：Developmental & Comparative Immunology
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：66
- 期：Complete
- 页码：61-72
- 全文大小：1683 K
文摘
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Carp leukocytes express nuclear – ER and membrane - GPR30 estrogen receptors.
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erβ is not-detectable in naïve PBL's.
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Immunostimulation alters the expression of estrogen receptors.
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E2-induced changes in ROS production are mediated by GPR30.
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Neuroendocrine-immune interaction via estrogen receptors is evolutionary conserved.
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