Diverse effects of G-protein-coupled free fatty acid receptors on the regulation of cellular functions in lung cancer cells
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- 作者：Tsubasa Kitaa ; Yui Kadochia ; Kaede Takahashia ; Kaori Fukushimaa ; Eri Yamasakia ; Taiki Uemotoa ; Miku Hiranea ; Nobuyuki Fukushimab ; Kanya Honokic ; Toshifumi Tsujiuchia ; ttujiuch@life.kindai.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：GPR120 ; GPR40 ; Cell motility ; Invasion ; Lung cancer
- 刊名：Experimental Cell Research
- 出版年：2016
- 出版时间：15 March 2016
- 年：2016
- 卷：342
- 期：2
- 页码：193-199
- 全文大小：1217 K
文摘
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GPR120 inhibited and GPR40 stimulate cell motile activity of human lung cancer cells.
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The cell motile activity of lung cancer cells is suppressed by GPR40 knockdown.
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MMP activation and angiogenesis are regulated by GPR120 and GPR40 in lung cancer cells.
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GPR120 and GPR40 expressions were decreased in the long-term cisplatin treated cells.
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GPR120 and GPR40 are involved in the regulation of cellular functions in lung cancer cells.