The acute effect of intravenous lipopolysaccharide injection on serum and intrafollicular HDL components and gene expression in granulosa cells of the bovine dominant follicle

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• 作者：Felipe Terres de Campos^a ; ¹ ; Joao Aveiro Alvarado Rincon^b ; ¹ ; Diego Andres Velasco Acosta^c ; Pedro Augusto Silva Silveira^a ; Jorgea Pradieé ; ^d ; Marcio Nunes Corrê ; a^b ; Bernardo Garziera Gasperin^a ; Luiz Francisco Machado Pfeifer^e ; Carlos Castilho Barros^f ; Ligia Margareth Cantareli Pegoraro^d ; Augusto Schneider^f ; ^{augusto.schneider@ufpel.edu.br}
• 关键词：Inflammation ; PON1 ; Steroidogenesis ; Cholesterol
• 刊名：Theriogenology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：89
• 期：Complete
• 页码：244-249
• 全文大小：526 K
• 卷排序：89

文摘

An intravenous LPS challenge induces an acute inflammatory response; LPS reduced expression of STAR, TLR4 and TNF mRNA in the dominant follicle granulosa cells; LPS reduced serum and intrafollicular PON1 activity; LPS reduced serum but not intrafollicular HDL-cholesterol concentrations.