Augmenter of liver regeneration (ALR) restrains concanavalin A-induced hepatitis in mice
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- 作者：Mao Mua ; b ; mumao0102@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Zhenwei Zhangb ; zhengwei-523@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Yi Chenga ; b ; chengyidyt@163.com" class="auth_mail" title="E-mail the corresponding author ; Guangze Liub ; lgze68@163.com" class="auth_mail" title="E-mail the corresponding author ; Xiusheng Chenb ; 13631341977@163.com" class="auth_mail" title="E-mail the corresponding author ; Xin Wua ; wuxin44771@163.com" class="auth_mail" title="E-mail the corresponding author ; Caifang Zhuangb ; 1003550116@qq.com" class="auth_mail" title="E-mail the corresponding author ; Bingying Liua ; liubingying530@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Xiangping Kongb ; xiangping_kong@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Song Youa ; yousong207@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Augmenter of liver regeneration ; Concanavalin A ; Hepatitis ; T cell activation ; MAPK ; NF-κB
- 刊名：International Immunopharmacology
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：35
- 期：Complete
- 页码：280-286
- 全文大小：950 K
文摘
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ALR restrains hepatitis via inhibiting of CD4+, CD8+ T cells infiltration.
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ALR reduces the secretion of pro-inflammatory cytokines and chemokines.
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ALR inhibits the activation of JNK, MAP kinase and NF-κB pathways in the hepatitis.
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ALR displays an extraordinary immunoregulatory effect.