Seasonality and temperature effects on fasting plasma glucose: A population-based longitudinal study in China

详细信息    查看全文

• 作者：S. Li^a ; ^{uqshandy0106@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Y. Zhou^b ; ^{yongzhou78214@163.com" class="auth_mail" title="E-mail the corresponding author} ; G. Williams^a ; ^{g.williams@sph.uq.edu.au" class="auth_mail" title="E-mail the corresponding author} ; J.J.K. Jaakkola^c ; ^{jouni.jaakkola@oulu.fi" class="auth_mail" title="E-mail the corresponding author} ; C. Ou^d ; ^{ouchunquan@hotmail.com" class="auth_mail" title="E-mail the corresponding author} ; S. Chen^e ; ^{chenshuohua0106@126.com" class="auth_mail" title="E-mail the corresponding author} ; T. Yao^f ; ^{ytc1963@163.com" class="auth_mail" title="E-mail the corresponding author} ; T. Qin^f ; ^{13831591818@126.com" class="auth_mail" title="E-mail the corresponding author} ; S. Wu^e ; ^{drwusl@163.com" class="auth_mail" title="E-mail the corresponding author} ; Y. Guo^a ; ^{y.guo1@uq.edu.au" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Diabetes ; Fasting plasma glucose ; Seasonality ; Temperature effect
• 刊名：Diabetes & Metabolism
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：42
• 期：4
• 页码：267-275
• 全文大小：357 K

文摘

To examine the seasonality and effects of temperature on levels of fasting plasma glucose (FPG).

Methods

We collected health data from the Kailuan cohort study. FPG, blood pressure and individual information including age, gender, body mass index, smoking status, drinking habit, physical activities, income, work type, education level, and history of diabetes, were collected for each participant. Daily weather conditions were collected during the study period of 2006–2011. A total of 49,417 participants who had three times of health examination were included to the analyses. Generalized additive mixed models were used to examine the effects of temperature and seasonality on FPG levels, while controlling for potential confounders.

Results

FPG level was higher in winter and spring than that in autumn and summer. For all participants, the FPG winter level increased 0.31 mmol/L [95% confidence interval (CI), 0.28–0.33 mmol/L] in comparison with autumn. The association between temperature and FPG levels was U-shaped. For all participants, the change in FPG levels associated with extreme cold temperature (−6.7 °C), moderate cold temperature (2.4 °C), moderate hot temperature (23.7 °C), and with extreme hot temperature (28.1 °C), in comparison with threshold (18.1 °C) were 0.12 mmol/L (95% CI: 0.10–0.14 mmol/L), 0.10 (95% CI: 0.09–0.12 mmol/L), 0.06 (95% CI: 0.04–0.08 mmol/L), and 0.12 mmol/L (95% CI: 0.08–0.16 mmol/L), respectively.

Conclusion

The findings suggest that there may be strong relationships between FPG levels and season and ambient temperature. In particular, there were higher FPG levels in the winter and at extreme cold and hot temperatures.