Ag nanoparticles cladded with parylene for high-stability microfluidic surface-enhanced Raman scattering (SERS) biochemical sensing

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• 作者：Jun TangAuthor Vitae ; Hao GuoAuthor Vitae ; Miaomiao ZhaoAuthor Vitae ; Wenyao LiuAuthor Vitae ; Xiujian ChouAuthor Vitae ; Binzhen ZhangAuthor Vitae ; Chenyang XueAuthor Vitae ; Wendong ZhangAuthor Vitae ; Jun Liu ; ^{liuj@nuc.edu.cn}Author Vitae
• 刊名：Sensors and Actuators B: Chemical
• 出版年：2017
• 出版时间：April 2017
• 年：2017
• 卷：242
• 期：Complete
• 页码：1171-1176
• 全文大小：2002 K
• 卷排序：242

文摘

The reusable microfluidic-integrated devices based on the Ag nanoparticles cladded with parylene was manufactured. Parylene Shell with a uniform and highly controlled thickness was manufactured. Ag nanoparticles cladded with parylene C exhibited excellent Raman enhancement effect comparing with the initial substrate. The parylene cladding film increased the repulsive to the molecular probes, enabling hundreds of measurement cycles and greatly increasing the stability and reproducibility.