Label-free liquid crystal biosensor for L-histidine: A DNAzyme-based platform for small molecule assay
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- 作者：Shuzhen Liao ; Huazhi Ding ; Yan Wu ; Zhaoyang Wu ; zywu@hnu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Guoli Shen ; Ruqin Yu
- 关键词：DNAzyme ; Liquid crytal ; Biosensor ; L-histidine ; DNA
- 刊名：Biosensors and Bioelectronics
- 出版年：2016
- 出版时间：15 May 2016
- 年：2016
- 卷：79
- 期：Complete
- 页码：650-655
- 全文大小：938 K
文摘
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This is the first DNAzyme-based liquid crystal biosensor for small molecule.
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L-histidine-mediated formation of ds-DNA causes an evident birefringent texture.
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This method is label-free and has no amplified procedure but with high sensitivity.