Validity of a Brazilian version of the Zung self-rating depression scale for screening of depression in patients with Parkinson's disease

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• 作者：Marcos Hortes Nisihara Chagas ; Vitor Tumas ; Sonia Regina Loureiro ; Jaime E.C. Hallak ; Clarissa Trzesniak ; Joã ; o Paulo Machado de Sousa ; Guilherme Gustavo Ricciopo Rodrigues ; Alaor Santos Filho ; Jo
• 关键词：Depression ; Scale ; Parkinson's disease ; Zung self-rating depression scale
• 刊名：Parkinsonism and Related Disorders
• 出版年：2010
• 出版时间：January 2010
• 年：2010
• 卷：16
• 期：1
• 页码：42-45
• 全文大小：154 K

文摘

class=""h4"">Introduction

Parkinson's disease (PD) is a neurodegenerative disorder with prominent motor manifestations and many other non-motor symptoms that significantly decrease quality-of-life and are frequently under-recognized, for example depression.

class=""h4"">Objective

To study the validity of a Brazilian version of the Zung Self-rating Depression Scale (SDS) for the diagnosis of depression in patients with PD.

class=""h4"">Methods

We evaluated 78 consecutive non demented patients over the age of 40 with diagnosis of PD at a Movement Disorders Outpatient Clinic, who could read and understand questionnaires. They completed the SDS and the Geriatric Depression Scale with 15 items (GDS-15). The diagnosis of depression was made after a structured clinical interview based on DSM-IV criteria for the diagnosis of major depression (SCID-CV).

class=""h4"">Results

The prevalence of major depression was 23.1 % . Cronbach's alpha was 0.73 and the area under the ROC curve was 0.93 for the SDS. The score index of 55 had a sensitivity of 88.9 % and a specificity of 83.3 % for the diagnosis of depression. The total scores of the SDS and GDS-15 were highly correlated (0.652, p c; 0.0001) and correlated weakly with the scores of a motor scale.

class=""h4"">Discussion

The SDS is a valid tool for screening depression in patients with PD since the specific SDS index of 55 is adopted. Two shortened versions could be used with good results.