Prospective study of direct radiation exposure measurements for family members living with patients with prostate ¹²⁵I seed implantation: Evidence of radiation safety

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• 作者：Takashi Hanada¹ ; ² ; ^{thanada@rad.med.keio.ac.jp" class="auth_mail" title="E-mail the corresponding author} ; Atsunori Yorozu² ; Yukiko Shinya² ; Nobuko Kuroiwa² ; Toshio Ohashi¹ ; Shiro Saito³ ; Naoyuki Shigematsu¹
• 关键词：Brachytherapy ; Iodine-125 ; Radiation exposure ; Prostate cancer ; Radiation safety
• 刊名：Brachytherapy
• 出版年：2016
• 出版时间：July-August 2016
• 年：2016
• 卷：15
• 期：4
• 页码：412-419
• 全文大小：1632 K

文摘

To broaden the current understanding of radiation exposure and risk and to provide concrete evidence of radiation safety related to ¹²⁵I seed implantation.

Methods and Materials

Direct radiation exposure measurements were obtained from dosimeters provided to 25 patients who underwent ¹²⁵I seed implantation, along with their family members. The estimated lifetime exposure dose and the precaution time for holding children near the patient's chest were calculated in two study periods.

Results

During the first and second study period, the mean estimated lifetime exposure doses were, respectively, 7.61 (range: 0.45, 20.21) mSv and 6.84 (range: 0.41, 19.20) mSv for patients, and 0.19 (range: 0.02, 0.54) mSv and 0.25 (range: 0.04, 1.00) mSv for family members. The mean ratios of first and second period measurements were 1.05 (range: 0.44, 3.18) for patients and 1.82 (range: 0.21, 7.04) for family members. The corresponding absolute differences between first and second period measurements were −0.77 (range: −11.40, 7.63) mSv and 0.06 (range: −0.26, 0.79) mSv, respectively. Assuming a dose limit of 1 mSv, the precaution times for holding a child every day of the first and second periods were 250.9 (range: 71.3, 849.4) min and 275.2 (range: 75.0, 883.4) min, respectively. Assuming a dose limit of 0.5 mSv, the corresponding precaution times were 179.0 (range: 35.6, 811.5) min and 178.9 (range: 37.5, 1131.8) min, respectively.

Conclusions

Our study demonstrated low radiation exposures to family members of patients undergoing ¹²⁵I prostate implantation. It was clear that ¹²⁵I seed implantation did not pose a threat to the safety of family members.