Increased expression of immune modulator proteins and decreased expression of apolipoprotein A-1 and haptoglobin in blood plasma of sarin exposed rats
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- 作者：Kalyani Chaubeya ; M. Kameshwar Raoa ; S. Imteyaz Alamb ; Chandrakant Waghmarea ; Bijoy K. Bhattacharyaa ; bkbhattacharya@rediffmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Sarin ; Plasma proteomics ; Apolipoprotein A-1 ; Haptoglobin ; Neurodegeneration
- 刊名：Chemico-Biological Interactions
- 出版年：2016
- 出版时间：25 February 2016
- 年：2016
- 卷：246
- 期：Complete
- 页码：36-44
- 全文大小：893 K
文摘
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Effect of sarin on plasma proteomic profile studied.
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Immune modulator proteins are over expressed on day one.
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Apolipoprotein A1 and Haptoglobin were down regulated on day seven.
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Decreased ApoA1 and Hp are early indications of neurodegenerative disorders.