Analytical challenges in the confirmative identification of dipyrone as an adulterant in illicit drug samples

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• 作者：Richard C.A. Isaacs ; ^{richard_isaacs@verizon.net} ; Michaela M. Harper ; Emily C. Miller
• 关键词：Dipyrone ; Aminopyrine ; 4-Methylaminoantipyrine ; Adulterant ; Fentanyl ; Mass Spectrometry
• 刊名：Forensic Science International
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：270
• 期：Complete
• 页码：185-192
• 全文大小：1096 K
• 卷排序：270

文摘

Dipyrone undergoes thermal and/or hydrolytic decomposition during GC and GC–MS analysis. There are two possible decomposition products: aminopyrine and 4-methylaminoantipyrine. NMR spectroscopy and ESI mass spectrometry can be used to confirm the presence of dipyrone. NMR spectroscopy can be used to confirm or refute the presence of dipyrone, aminopyrine and 4-methylaminoantipyrine.