Isolation and characterization of alborixin from Streptomyces scabrisporus: A potent cytotoxic agent against human colon (HCT-116) cancer cells
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- 作者：Aabid Manzoor Shaha ; d ; Abubakar Wanib ; d ; Parvaiz H. Qazia ; d ; qphassan@iiim.ac.in" class="auth_mail" title="E-mail the corresponding author ; Shakeel-u Rehmanc ; Saleem Mushtaqa ; Shiekh Abid Alia ; Aehtesham Hussaina ; d ; Aiyatullah Shaha ; d ; Asif Khurshid Qazib ; Ubaid Sharif Makhdoomib ; d ; Abid Hamidb ; d ; Ajay Kumarb ; d
- 关键词：Kashmir Himalayas ; Streptomyces scabrisporus ; Alborixin ; Anticancer ; HCT-116 ; Apoptosis
- 刊名：Chemico-Biological Interactions
- 出版年：2016
- 出版时间：25 August 2016
- 年：2016
- 卷：256
- 期：Complete
- 页码：198-208
- 全文大小：2689 K
文摘
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Isolation of actinomycetes from soil samples collected from Kashmir Himalayas.
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Screening of actinomycetes for cytotoxic activity.
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Identification and phylogenetic analysis of potent Strain (IIIM55).
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Isolation and structure elucidation of the bioactive compound from the Streptomyces scabrisporus (IIIM55).
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Assessment of anti-cancerous activity of purified compound (alborixin).