Clinical validation of a novel diagnostic HIV-2 total nucleic acid qualitative assay using the Abbott m2000 platform: Implications for complementary HIV-2 nucleic acid testing for the CDC 4th generation HIV diagnostic testing algorithm

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• 作者：Ming Chang^a ; Audrey J.S. Wong^a ; Dana N. Raugi^b ; Robert A. Smith^b ; Annette M. Seilie^a ; Jose P. Ortega^a ; Kyle M. Bogusz^a ; Fatima Sall^c ; Selly Ba^c ; Moussa Seydi^c ; Geoffrey S. Gottlieb^b ; ^d ; Robert W. Coombs^a ; ^b ; ^{bcoombs@u.washington.edu}
• 关键词：HIV-2 ; Diagnostic ; Qualitative ; Total nucleic acid ; DNA/RNA ; PCR
• 刊名：Journal of Clinical Virology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：86
• 期：Complete
• 页码：56-61
• 全文大小：401 K
• 卷排序：86

文摘

A qualitative assay detecting HIV-2 total nucleic acid in patients’ PBMCs. A second-line assay to resolve HIV-2 sero-indeterminate cases. Able to detect HIV-2 DNA and RNA in PBMC from patients with undetected plasma RNA.