Marijuana effects on changes in brain structure and cognitive function among HIV+ and HIV− adults

详细信息    查看全文

• 作者：April D. Thames^a ; ¹ ; ^{athames@mednet.ucla.edu} ; Taylor P. Kuhn^a ; ¹ ; Timothy J. Williamson^b ; Jacob D. Jones^a ; Zanjbeel Mahmood^a ; Andrea Hammond^a ; ^c
• 关键词：HIV ; Magnetic resonance imaging ; Cognition ; Marijuana ; Cannabis
• 刊名：Drug and Alcohol Dependence
• 出版年：2017
• 出版时间：1 January 2017
• 年：2017
• 卷：170
• 期：Complete
• 页码：120-127
• 全文大小：939 K
• 卷排序：170

文摘

We examined the effects of HIV status and marijuana use on brain structure and neurocognitive function. For HIV+ and HIV- participants, higher levels of MJ use were associated with smaller volumes in the entorhinal cortex and fusiform gyrus. When MJ use was <1.43g/week, HIV+ is related to worse cognitive performance. When MJ use was >1.43g/week, the HIV+ and HIV- did not differ in cognitive function.