TLR response pathways in NuLi-1 cells and primary human nasal epithelial cells
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- 作者：Clare Cooksley ; Eugene Roscioli ; Peter John Wormald ; Sarah Vreugde ; sarah.vreugde@adelaide.edu.au" class="auth_mail" title="E-mail the corresponding author
- 关键词：HNECs ; human nasal epithelial cells ; ALI ; air-liquid interface ; TLR ; toll-like receptor
- 刊名：Molecular Immunology
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：68
- 期：2
- 页码：476-483
- 全文大小：968 K
文摘
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TLR 1-9 mRNA expression was conserved in NuLi-1 and HNECs.
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Several TLR related genes were differentially expressed in NuLi-1 cells vs HNECs.
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The two cell types showed a conserved response to TLR3 agonists.
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NuLi-1 cells did not exhibit differentiation at air-liquid interface.
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HNECs were more susceptible to infection by S. aureus than NuLi-1 cells.