Cellular blue nevus (CBN) lymph node metastases of the neck with no primary skin lesion: A case report and review of literature

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• 作者：Konstanze Scheller ; Christian Scheller ; Susann Becker ; Hans-Jü ; rgen Holzhausen ; Johannes Schubert
• 关键词：cellular blue nevus (CBN) lymph node metastases ; no malignant transformation ; no primary skin-lesion
• 刊名：Journal of Cranio-Maxillofacial Surgery
• 出版年：2010
• 出版时间：December 2010
• 年：2010
• 卷：38
• 期：8
• 页码：601-604
• 全文大小：1082 K

文摘

Summary

A case of cervical lymph node infiltration by a benign cellular blue nevus (CBN) and a 27-year disease history is presented.

Dermal dendritic melanocytes and pigmented spindle cells presented no histological evidence of malignancy (CD34−, desmin−, PanCy−, HMB-45+, anti-S-100+, Bcl-2+, MART-1+, focally expression of melan A, 1 % Ki-67+ of the tumour cell nucleoli).

The differentiation of the benign blue nevus (BN) from a malignant blue nevus (MBN) and a malignant melanoma (MM) is still a challenge. Because of the malignant transformation potential of 5.2–6.3 % a histological examination and a conservative surgical approach with close follow up are mandatory.