Epilepsy-associated genes

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• 作者：Jie Wang^a ; ^b ; ¹ ; Zhi-Jian Lin^a ; ^b ; ¹ ; Liu Liu^a ; ^b ; Hai-Qing Xu^a ; ^b ; ^c ; Yi-Wu Shi^a ; ^b ; Yong-Hong Yi^a ; ^b ; Na He^a ; ^b ; ^{henachilli@163.com} ; Wei-Ping Liao^a ; ^b ; ² ; ^{wpliao@163.net} ; ^{wpliao@tom.com}
• 关键词：Epilepsy ; Epilepsy gene ; Epilepsy-related gene ; Genetics ; Phenotypes ; Gene function
• 刊名：Seizure
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：44
• 期：Complete
• 页码：11-20
• 全文大小：371 K
• 卷排序：44

文摘

We summarized 977 epilepsy-associated genes, which were divided into 4 categories according to the manifestation of epilepsy in phenotypes. 84 epilepsy genes, i.e., genes that only cause epilepsies or syndromes with epilepsy as the core symptom. 73 neurodevelopment-associated genes, i.e., genes associated with gross brain developmental malformations and epilepsies. 536 epilepsy-related genes, i.e., genes associated with gross physical, or other systemic abnormalities and accompanied by epilepsy or seizures. 284 potential epilepsy-associated genes, i.e., genes that require further verification.