Antibacterial mechanism of daptomycin antibiotic against Staphylococcus aureus based on a quantitative bacterial proteome analysis
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- 作者：Wen Maa ; Dan Zhanga ; Guoshun Lia ; Jingjing Liua ; Gu Hea ; Peng Zhangb ; Li Yanga ; Hongxia Zhuc ; Ningzhi Xua ; c ; Shufang Lianga ; zizi2006@scu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Daptomycin ; Staphylococcus aureus ; Antibacterial activity ; Quantitative proteomic
- 刊名：Journal of Proteomics
- 出版年：2017
- 出版时间：6 January 2017
- 年：2017
- 卷：150
- 期：Complete
- 页码：242-251
- 全文大小：1364 K
文摘
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Fifty-one bacterial proteins were alerted against daptomycin by iTRAQ analysis.
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The variation tendency of NDK and NT5 is consistent in pathogenetic bacteria.
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Daptomycin induces some physiological changes of Staphylococcus aureus.