Identification and characterization of a novel Toll-like receptor 4 homologue in blunt snout bream, Megalobrama amblycephala
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- 作者：Leilei Tanga ; 1 ; Xinying Xiangb ; 1 ; Yuhong Jianga ; Yina Lva ; Yi Zhouc ; Huan Zhongc ; Jun Xiaoc ; Fuyun Zhanga ; Hongyang Jianga ; Jinpeng Yana ; andy_yan@csu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Megalobrama amblycephala ; Toll-like receptor 4 ; Lipopolysaccharide stimulation ; Immune response
- 刊名：Fish & Shellfish Immunology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：57
- 期：Complete
- 页码：25-34
- 全文大小：3081 K
文摘
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A novel TLR4 homologue was identified and characterized in blunt snout bream.
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Phylogenetic analysis indicated the existence of two different TLR4 homologues in blunt snout bream.
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MaTLR4b was significantly up-regulated in spleen after LPS stimulation.
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MaTLR4s may play an important role in antibacterial immunity.