Molecular epidemiology of multidrug-resistant Acinetobacter baumannii isolates in a university hospital in Nepal reveals the emergence of a novel epidemic clonal lineage
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- 作者：Shovita Shresthaa ; 1 ; Tatsuya Tadab ; 1 ; Tohru Miyoshi-Akiyamac ; Hiroshi Oharad ; Kayo Shimadab ; Kazuhito Satoue ; Kuniko Teruyae ; Kazuma Nakanoe ; Akino Shiromae ; Jeevan Bdr. Sherchanda ; Basista Psd. Rijala ; Takashi Hiranoe ; Teruo Kirikaeb ; tkirikae@ri.ncgm.go.jp" class="auth_mail" title="E-mail the corresponding author ; Bharat Mani Pokhrela
- 关键词：Multidrug-resistant Acinetobacter baumannii ; 16S rRNA methylase ; Carbapenemase ; Molecular epidemiology ; Clonal complex
- 刊名：International Journal of Antimicrobial Agents
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：46
- 期：5
- 页码：526-531
- 全文大小：910 K
文摘
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Three major clonal lineages (CC1, CC2 and CC149) were detected among multidrug-resistant (MDR) Acinetobacter baumannii isolates at a single institution.
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The complete genome of one A. baumannii isolate belonging to the novel CC149 clonal lineage was sequenced.
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These isolates contained NDM-1, OXA-23 or OXA-58 carbapenemases and 16S rRNA methylase ArmA.
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MDR and extensively drug-resistant (XDR) susceptibility profiles were determined for these isolates.