FCN2 inhibits epithelial-mesenchymal transition-induced metastasis of hepatocellular carcinoma via TGF-β/Smad signaling
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- 作者：Guangchao Yang1 ; Yingjian Liang1 ; Tongsen Zheng ; Ruipeng Song ; Jiabei Wang ; Huawen Shi ; Boshi Sun ; Changming Xie ; Yuejin Li ; Jihua Han ; Shangha Pan ; Yaliang Lan ; Xirui Liu ; Mingxi Zhu ; Yan Wang ; Lianxin Liu ; liulianxin@ems.hrbmu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Hepatocellular carcinoma ; FCN2 ; EMT ; TGF β
- 刊名：Cancer Letters
- 出版年：2016
- 出版时间：10 August 2016
- 年：2016
- 卷：378
- 期：2
- 页码：80-86
- 全文大小：2702 K
文摘
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FCN2 can inhibit HCC invasion and metastasis.
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FCN2 exerts its functions through inhibiting EMT.
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FCN2 can block EMT induced by TGFβ/Smad pathway in HCC.