IRF3 is involved in human acute myeloid leukemia through regulating the expression of miR-155
详细信息 查看全文
- 作者：Wen-Liang Tian ; Zhong-Xing Jiang ; Fang Wang ; Rong Guo ; Ping Tang ; Yu-Min Huang ; Ling Sun ; lingsun1@21cn.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：IRF3 ; Acute myeloid leukemia ; miR-155
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：23 September 2016
- 年：2016
- 卷：478
- 期：3
- 页码：1130-1135
- 全文大小：962 K
文摘
- •
IRF3 is overexpressed in human AML.
- •
IRF3 promotes AML cell proliferation and colony formation.
- •
IRF3 maintains cell survival of AML cells.
- •
IRF3 regulates the expression of miR-155.