Codon usage pattern and prediction of gene expression level in Bungarus species

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• 作者：Supriyo Chakraborty^a ; ^{supriyoch_2008@rediffmail.com} ; Debojyoti Nag^a ; Tarikul Huda Mazumder^a ; Arif Uddin^a ; ^b
• 关键词：ENCs ; effective number of codons ; CAI ; codon adaptation index ; RSCU ; relative synonymous codon usage
• 刊名：Gene
• 出版年：2017
• 出版时间：10 March 2017
• 年：2017
• 卷：604
• 期：Complete
• 页码：48-60
• 全文大小：2175 K
• 卷排序：604

文摘

Our codon usage bias was low in four species of Bungarus. The compositional constraints together with gene expression level might influence the patterns of codon usage among the genes of Bungarus species. The codon usage patterns of the genes in B. multicinctus share similarity with that of B. candidus while B. fasciatus with B. flaviceps. Nature favours the most over-represented codon AGA (arginine), GGA (glycine), CTG (leucine) and TCT (serine) in B. multicinctus, B. candidus, B. flaviceps and B. fasciatus respectively. Both natural selection and mutation pressure affect the codon usage pattern in Bungarus species. Natural selection played a major role while mutation pressure played a minor role in the codon usage pattern of the genes in Bungarus species.