Retinal imaging and axonal degeneration in later onset multiple sclerosis
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- 作者：Konstantin Huhn ; MDa ; Konstantin.Huhn@uk-erlangen.de" class="auth_mail" title="E-mail the corresponding author ; Robert Lä ; mmer ; MDb ; Hanna Zimmermann ; MEngc ; Alexandra Lä ; mmer ; MDa ; Anne Waschbisch ; MDa ; Kathrin Utz ; PhDa ; René ; Markus Gieß ; c ; Friedemann Paul ; MDc ; Ralf A. Linker ; MDa ; 1 ; De-Hyung Lee ; MDa ; 1
- 关键词：Late onset multiple sclerosis ; Neuroophthalmology ; Optical coherence tomography
- 刊名：Journal of the Neurological Sciences
- 出版年：2016
- 出版时间：15 November 2016
- 年：2016
- 卷：370
- 期：Complete
- 页码：1-6
- 全文大小：242 K
文摘
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Late onset MS is rare and few is known about neuro-retinal degeneration.
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OCT is a non-invasive method for measuring neuro-retinal degeneration in vivo.
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LOMS eyes display lower retinal layer thickness than healthy controls.
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Previous optic neuritis is a main contributor to retinal layer degeneration.
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In LOMS, levels of neuro-retinal degeneration are similar to age- or disease duration-matched NOMS.