MicroRNA-506-3p regulates neural stem cell proliferation and differentiation through targeting TCF3
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- 作者：Yan Wang ; Chen Jiaqi ; Chen Zhaoying ; Chen Huimin ; huiminchennb@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：NSCs ; neural stem cells ; miRNAs ; microRNAs ; siRNA ; interfering RNA ; ESC ; embryonic stem cell ; HEK ; human embryonic kidney ; GFAP ; glial fibrillary acidic protein ; Tuj1 ; Neuronal Class III β-Tubulin
- 刊名：Gene
- 出版年：2016
- 出版时间：15 November 2016
- 年：2016
- 卷：593
- 期：1
- 页码：193-200
- 全文大小：986 K
文摘
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MiR-506-3p is increased during NSC differentiation.
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MiR-506-3p modulates cell proliferation and differentiation of NSCs
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MiR-506-3p targets TCF3 and decreases its expression in NSC cells.
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TCF3 is involved in miR-506-3p regulated proliferation and differentiation in NSC cells.