A novel modeling method to evaluate the bioactive contributions of compositions in traditional Chinese medicine
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- 作者：Erxin Shang ; Shulan Su ; Huiting Zeng ; Zhenhua Zhu ; Jinao Duan
- 关键词：Pharmacological modeling ; Bioactivity prediction ; Bioactivity evaluation ; Herbal extracts ; Traditional Chinese medicine
- 刊名：Chemometrics and Intelligent Laboratory Systems
- 出版年：2016
- 出版时间：15 December 2016
- 年：2016
- 卷：159
- 期：Complete
- 页码：151-154
- 全文大小：586 K
- 卷排序：159
文摘
A new method to evaluate component's bioactive contribution in TCM was proposed. The sigmoid function was selected to fit extracts and components bioactive data. Nonlinear LSQ optimization was used to predict bioactive strength and contribution.