Understanding the effect of hydrophobic protecting blocks on the stability and biopassivity of polymer brushes in aqueous environments: A Tiramisù for cell-culture applications
详细信息 查看全文
- 作者：Mohammad Divandaria ; Ella S. Dehghania ; Nicholas D. Spencera ; nspencer@ethz.ch" class="auth_mail" title="E-mail the corresponding author ; Shivaprakash N. Ramakrishnaa ; Edmondo M. Benettia ; b ; edmondo.benetti@mat.ethz.ch" class="auth_mail" title="E-mail the corresponding author
- 关键词：Polymer brush ; Antibiofouling ; Atomic force microscopy ; Block copolymer ; ATRP
- 刊名：Polymer
- 出版年：2016
- 出版时间：19 August 2016
- 年：2016
- 卷：98
- 期：Complete
- 页码：470-480
- 全文大小：3217 K
文摘
•Synthesis and characterization of diblock-copolymer brushes aimed at cell-culture experiments.
•Diblock copolymers had a hydrophobic, substrate-bound layer and a hydrophilic interfacial brush.
•Effect of the hydrophobic block on biopassivity and stability in cell-culture medium was determined.
•Higher stiffness and the hydrophobicity of substrate-bound block improved stability of system compared to brush alone.
•Grafting density of the substrate-bound layer was the main factor determining biopassivity.