Chemical fingerprint and metabolic profile analysis of ethyl acetate fraction of Gastrodia elata by ultra performance liquid chromatography/quadrupole-time of flight mass spectrometry
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- 作者：Chunlan Tanga ; b ; Li Wanga ; Xinxin Liua ; Mengchun Chenga ; Hongbin Xiaoc ; hbxiao@dicp.ac.cn" class="auth_mail" title="E-mail the corresponding author ; hbxiao69@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：p-Hydroxybenzaldehyde (PubChem CID ; 126) ; 3 ; 4-Dihydroxy benzaldehyde (PubChem CID ; 8768) ; p-Hydroxybenzyl alcohol (PubChem CID ; 125) ; p-Hydroxybenzoic acid (PubChem CID ; 135) ; 4 ; 4-Dihydroxydiphenylmethane (PubChem CID ; 12111)
- 刊名：Journal of Chromatography B, Analytical Technologies in the Biomedical and Life Sciences
- 出版年：2016
- 出版时间：1 February 2016
- 年：2016
- 卷：1011
- 期：Complete
- 页码：233-239
- 全文大小：607 K
文摘
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Thirty eight constituents in ethyl acetate fraction of Gastrodia elata were identified or tentatively characterized.
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Forty compounds including sixteen prototypes and twenty four metabolites were detected in dosed rat plasma sample.
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The main metabolic “soft spots” was hydroxyl or carboxyl group.