The Spanish Standard Patch Test Series: 2016 Update by the Spanish Contact Dermatitis and Skin Allergy Research Group (GEIDAC)

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• 作者：M. Hervella-Garcé ; s^a ; ^{marcoshervellag@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; J. Garcí ; a-Gaví ; n^b ; J.F. Silvestre-Salvador^c ; en representació ; n del Grupo Españ ; ol de Investigació ; n en Dermatitis de Contacto y Alergia Cutá ; nea (GEIDAC)¹
• 关键词：Epidemiology ; Allergic contact dermatitis ; Type IV hypersensitivity ; Skin tests ; Patch tests ; Hapten
• 刊名：Actas Dermo-Sifiliográficas (English Edition)
• 出版年：2016
• 出版时间：September 2016
• 年：2016
• 卷：107
• 期：7
• 页码：559-566
• 全文大小：579 K

文摘

The Spanish standard patch test series, as recommended by the Spanish Contact Dermatitis and Skin Allergy Research Group (GEIDAC), has been updated for 2016. The new series replaces the 2012 version and contains the minimum set of allergens recommended for routine investigation of contact allergy in Spain from 2016 onwards.

Four haptens —clioquinol, thimerosal, mercury, and primin—have been eliminated owing to a low frequency of relevant allergic reactions, while 3 new allergens —methylisothiazolinone, diazolidinyl urea, and imidazolidinyl urea—have been added. GEIDAC has also modified the recommended aqueous solution concentrations for the 2 classic, major haptens methylchloroisothiazolinone/methylisothiazolinone mix, which is now to be tested at 200 ppm in aqueous solution, and formaldehyde, which is now to be tested in a 2% aqueous solution.

Updating the Spanish standard series is one of the functions of GEIDAC, which is responsible for ensuring that the standard series is suited to the country's epidemiological profile and pattern of contact sensitization.