Perinatal hypothalamic-pituitary-adrenal axis regulation among women with eating disorders and their infants

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• 作者：A. Easter^a ; ^b ; ^c ; ^{abigail.easter@kcl.ac.uk} ; E. Taborelli^a ; ^b ; A. Bye^a ; ^b ; ^c ; P.A. Zunszain^d ; C.M. Pariante^d ; J. Treasure^b ; U. Schmidt^b ; N. Micali^a ; ^e ; ^f
• 关键词：Perinatal ; Eating disorders ; Stress ; Pregnancy ; Hypothalamic-pituitary-adrenal axis ; Cortisol ; Infant
• 刊名：Psychoneuroendocrinology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：76
• 期：Complete
• 页码：127-134
• 全文大小：737 K
• 卷排序：76

文摘

Eating disorders can affect pregnancy outcomes and impact on child development. Foetal programming is a potential mechanism for these outcomes. During pregnancy women with eating disorders show blunted diurnal cortisol rhythms. In the postnatal period their infants also have a heightened response to stress. Indicating intergenerational effects of hypothalamic-pituitary-adrenal axis dysfunction.