Water-insoluble thin films from palmitoyl hyaluronan with tunable properties
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- 作者：Marcela Foglarová ; a ; Marcela.Foglarova@contipro.com" class="auth_mail" title="E-mail the corresponding author ; Josef Chmelařa ; Gloria Huerta-Angelesb ; Hana Vá ; gnerová ; b ; Jaromí ; r Kulhá ; nekb ; Kateřina Bartoň Tomá ; nková ; c ; Antoní ; n Minaří ; kd ; Vladimí ; r Velebný ; a
- 关键词：Palmitoyl hyaluronan ; Thin film ; Solution casting ; Tensile properties ; Swelling
- 刊名：Carbohydrate Polymers
- 出版年：2016
- 出版时间：25 June 2016
- 年：2016
- 卷：144
- 期：Complete
- 页码：68-75
- 全文大小：1880 K
文摘
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We developed water-insoluble thin films from palmitoyl hyaluronan (pHA).
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Insolubility by improved pHA synthesis: higher substitution degrees now possible.
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Film behavior can be tuned by using pHA with suitable MW and substitution degree.
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In vitro experiments: pHA films are non-cytotoxic and show no adhesion of cells.
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Results suggest that pHA films are promising materials for biomedical applications.