A total of 88 ICUs from 36 Turkish tertiary hospitals were included in this retrospective study, which was performed during the first 3 months of both 2008 (period [P] 1) and 2011 (P2). A <em>Pem> value 鈮?01 was considered significant.
Although overall rates of hospital-acquired infection (HAI) and device-associated infection densities were similar in P1 and P2, the densities of HAIs due to <em>S aureusem> and methicillin-resistant <em>S聽aureusem> (MRSA) were significantly lower in P2 (<em>Pem> < .0001). However, the proportion of HAIs due to <em>Acinetobacterem> was significantly higher in P2 (<em>Pem> < .0001).
The incidence of <em>S aureusem> infections is declining rapidly in Turkish ICUs, with potential impacts on empirical treatment strategies in these ICUs.