The CD47 “don't eat me signal” is highly expressed in human ovarian cancer
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- 作者：R.M. Brightwella ; b ; K.S. Grzankowskia ; b ; S. Lelea ; K. Engc ; M. Arshadd ; H. Chend ; K. Odunsia ; b ; kunle.odunsi@roswellpark.org" class="auth_mail" title="E-mail the corresponding author
- 关键词：EOC ; epithelial ovarian cancer ; TMA ; tissue microarray ; TCGA ; the cancer genome atlas ; IHC ; immunohistochemistry ; OS ; overall survival ; SIRPα ; signal regulatory protein alpha ; FFPE ; formalin-fixed paraffin-embedded ; WHO ; World Health Organization
- 刊名：Gynecologic Oncology
- 出版年：2016
- 出版时间：November 2016
- 年：2016
- 卷：143
- 期：2
- 页码：393-397
- 全文大小：956 K
文摘
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CD47 serves as a “don't eat me signal.”
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5% of ovarian cancers profiled had an alteration of the CD47 gene in the TCGA dataset.
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Low CD47 expression correlates with complete response to therapy.
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