A highly selective nanocomposite based on MIP for curcumin trace levels quantification in food samples and human plasma following optimization by central composite design

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• 作者：Sonia Bahrani^a ; Mehrorang Ghaedi^a ; ^{m_ghaedi@mail.yu.ac.ir} ; Mohammad Javad Khoshnood Mansoorkhani^b ; Abbas Ostovan^c
• 关键词：Central composite design ; Curcumin ; HPLC-UV ; Magnetic multiwalled carbon nanotubes ; Molecularly imprinted polymer
• 刊名：Journal of Chromatography B
• 出版年：2017
• 出版时间：1 January 2017
• 年：2017
• 卷：1040
• 期：Complete
• 页码：129-135
• 全文大小：1962 K
• 卷排序：1040

文摘

A simple method was proposed to determine of curcumin in biological samples. The method is based on MSPE combined with HPLC-UV. The effective parameters in MSPE were optimized using RSM based on CCD. The applicability of the new proposed method was demonstrated in real samples. The figures of merit for curcumin in food samples were excellent.