Body mass index reference charts for individuals with Down syndrome aged 2-18 years

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• 作者：Fabio Bertapelli^a ; ^{fbertapelli@gmail.com} ; Maira R. Machado^a ; Raí ; sa do Val Roso^a ; Gil Guerra-Jú ; nior^b
• 关键词：Trisomy 21 ; Body mass index ; Weight ; Height ; Growth charts ; Nutritional status
• 刊名：Jornal de Pediatria
• 出版年：2017
• 出版时间：January-February 2017
• 年：2017
• 卷：93
• 期：1
• 页码：94-99
• 全文大小：1284 K
• 卷排序：93

文摘

To develop Brazilian growth charts for body mass index (BMI-for-age) for individuals with Down syndrome (DS). The secondary objective was to compare the BMI-for-age with the Centers for Disease Control and Prevention standards (CDC).MethodsA retrospective and cross-sectional growth study of 706 youth with DS (56.7% males) was performed in 51 centers in São Paulo state, Brazil. Weight and height were used to calculate the BMI (kg/m2). The LMS method was applied to construct the growth charts. Z-scores were based on the CDC 2000 growth standards.ResultsThe BMI-for-age reference charts showed excellent goodness of fit statistics for boys and girls with DS aged 2–18 years. At 2 years of age, the mean BMI Z-scores of boys and girls with DS were lower compared to those of the CDC (Z-score = −0.2). In contrast, children with DS aged 3–18 years had higher mean Z-scores for BMI-for-age when compared to those of the CDC (Z-scores = +0.2 to +1.3).ConclusionsThe BMI of Brazilian youth with DS differs from those references established by CDC. These are the first Brazilian BMI-for-age charts for individuals with DS and will hopefully guide clinicians and parents in the evaluation and management of the nutritional status in children and adolescents with DS in Brazil.