Quantitative mapping of cerebrovascular reactivity using resting-state BOLD fMRI: Validation in healthy adults
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- 作者：Ali M. Golestania ; Luxi L. Weia ; b ; 1 ; J. Jean Chena ; c ; jchen@research.baycrest.org" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cerebrovascular reactivity ; Resting-state fMRI ; End-tidal CO2 ; Respiratory-volume variability ; Heart-rate variability ; Deconvolution ; Hemodynamic response function ; Non-invasive vascular mapping
- 刊名：NeuroImage
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：138
- 期：Complete
- 页码：147-163
- 全文大小：2826 K
文摘
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We propose a novel method to quantify cerebrovascular reactivity (CVR) using resting-state fMRI.
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We map CVR using intrinsic CO2 fluctuations.
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We demonstrate good spatial agreement between our method and the CO2-inhalation method.
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We demonstrate reasonable repeatability of our method.
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Our method does not require any task and is well suited to large-scale patient studies.