Enhanced recovery of breathing capacity from combined adenosine 2A receptor inhibition and daily acute intermittent hypoxia after chronic cervical spinal injury
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- 作者：A. Navarrete-Opazoa ; b ; B.J. Doughertya ; G.S. Mitchella ; c ; gsmitche@phhp.ufl.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Intermittent hypoxia ; Spinal cord injury ; Chronic ; Functional recovery ; Breathing ; Spinal plasticity ; Adenosine receptors ; Rehabilitation ; Hemisection ; Cervical
- 刊名：Experimental Neurology
- 出版年：2017
- 出版时间：January 2017
- 年：2017
- 卷：287
- 期：part_P2
- 页码：93-101
- 全文大小：1225 K
文摘
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Daily intermittent hypoxia (dAIH) enhances ventilatory capacity in chronic cervical spinal injury.
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dAIH increases bilateral diaphragm activity in chronic cervical spinal injury.
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Adenosine 2A receptor inhibition enhances dAIH effects on diaphragm not T2 intercostal activity.
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Combined dAIH/A2A inhibition may benefit patients with chronic, incomplete cervical injuries.
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