Leptomeningeal metastasis from gynecologic cancers diagnosed by brain MRI

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• 作者：Masafumi Toyoshima^a ; ^b ; ^{m-toyo@med.tohoku.ac.jp} ; ^{masafumitoyoshima@gmail.com} ; Keita Tsuji^a ; Shogo Shigeta^a ; Hideki Tokunaga^a ; Kiyoshi Ito^c ; Yoh Watanabe^a ; Kosuke Yoshinaga^b ; Takeo Otsuki^a ; ¹ ; Hitoshi Niikura^a ; Nobuo Yaegashi^a
• 关键词：Carcinomatous meningitis ; Cytology ; Gynecologic cancers ; Leptomeningeal metastasis ; Magnetic resonance imaging
• 刊名：Clinical Imaging
• 出版年：2017
• 出版时间：January-February 2017
• 年：2017
• 卷：41
• 期：Complete
• 页码：42-47
• 全文大小：684 K
• 卷排序：41

文摘

Leptomeningeal metastasis (LM) is rarely observed in gynecologic cancers. As gadolinium-enhanced magnetic resonance imaging (Gd-MRI) is highly effective for diagnosing LM, the aim of this study is to describe the clinical behaviors and outcomes of LM patients who were diagnosed by Gd-MRI. After securing institutional review board approvals, we retrospectively reviewed patient records. Eight patients were found to have LM from gynecological malignancies. Primary tumors included three ovarian cancers, one tubal cancer, one peritoneal cancer, two endometrial cancers, and one cervical cancer. Gd-MRI of the brain and the spine is indicated as the high-priority inspection for the diagnosis of this devastating complication.